Sodium chloride is white or almost white, crystalline powder or colourless crystals or white or almost white pearls. This drug is highly soluble in water, and practically insoluble in anhydrous ethanol. The appearance of solution is clearand colorless. The dried product of this drug contains 99.0%to 100.5% sodium chloride (NaCl) when quantified.
Specification of Sodium Chloride
| Item |
Limited |
| Characteristics |
A white crystalline powder or colourless crystals , freely soluble in water, practically insoluble in alcohol. |
| Identification |
It gives reaction(a) of chloride . It gives reaction (a) of sodium. |
| Loss on drying |
Not more than 0.5% |
| Acidity /Alkalinity |
Conform |
| Appearance of Solution |
Solution S is clear and colourless. |
| Potassium |
Not more than 0.0002% |
| Barium |
Conform |
| Iron |
Not more than 0.0002% |
| Magnesium and alkkaline-earth metals |
Not more than 0.01% |
| Bromides |
Not more than 0.005% |
| Iodides |
The mixture shows no blue colour. |
| Sulphate |
Not more than 0.02% |
| Heavy metals |
Not more than 0.0005% |
| Aluminium |
Not more than 0.00002% |
| Ferrocyanides |
No blue colour develops within 10 min |
| Phosphates |
Not more than 0.0025% |
| Nitrites |
The absorbance is not more than 0.01 |
| Bacterial endotoxins |
Not more than 2.5IU/G |
| Microbial limit |
Not more than 100cfu/g |
| Assay |
99.0%-100.5% |
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